10/08/2009
Swine Flu Drug 'Less Effective' On Children
Children should not be given the anti-viral drug Tamiflu as it can have a limited effect on reducing swine flu, researchers have said.
The report from the British Medical Journal (BMJ) called upon the Department of Health to have an urgent rethink of its current policy in the H1N1 pandemic.
According to the BMJ anti-viral drugs like Tamiflu and Relenza rarely prevent complications in children with seasonal flu, but they do carry side effects.
Researchers analysed studies involving children aged between one and 12 taking one of the anti-virals. It found that the drug could cause vomiting, which could lead to dehydration and other complications.
There is also the risk that widespread use of the drugs will mean the flu virus will develop resistance to them.
Adding to this, the drug could have little or no effect on asthma flare-ups, ear infections or the likelihood of a child needing antibiotics.
The University of Oxford team, led by Dr Matthew Thompson carried out the research, which consisted of four trials on the treatment of seasonal flu in 1,766 children and three trials involving the use of antiviral to limit the spread of seasonal flu in 863 children.
"While morbidity and mortality in the current pandemic remain low, a more conservative strategy might be considered prudent, given the limited data, side effects such as vomiting, and the potential for developing resistant strains of influenza," the authors said.
Dr Thompson added: "Our research is finding for most children these antiviral drugs are probably not going to have much of an effect."
A Department of Health spokesman responded to the report: "The BMJ review is based on seasonal flu and not swine flu... the extent which the findings can be applied to the current pandemic is questionable.
"Whilst there is a doubt about how swine flu affects children, we believe a safety-first approach of offering anti-virals to everyone remains a sensible and responsible way forward."
(JM/BMcC)
The report from the British Medical Journal (BMJ) called upon the Department of Health to have an urgent rethink of its current policy in the H1N1 pandemic.
According to the BMJ anti-viral drugs like Tamiflu and Relenza rarely prevent complications in children with seasonal flu, but they do carry side effects.
Researchers analysed studies involving children aged between one and 12 taking one of the anti-virals. It found that the drug could cause vomiting, which could lead to dehydration and other complications.
There is also the risk that widespread use of the drugs will mean the flu virus will develop resistance to them.
Adding to this, the drug could have little or no effect on asthma flare-ups, ear infections or the likelihood of a child needing antibiotics.
The University of Oxford team, led by Dr Matthew Thompson carried out the research, which consisted of four trials on the treatment of seasonal flu in 1,766 children and three trials involving the use of antiviral to limit the spread of seasonal flu in 863 children.
"While morbidity and mortality in the current pandemic remain low, a more conservative strategy might be considered prudent, given the limited data, side effects such as vomiting, and the potential for developing resistant strains of influenza," the authors said.
Dr Thompson added: "Our research is finding for most children these antiviral drugs are probably not going to have much of an effect."
A Department of Health spokesman responded to the report: "The BMJ review is based on seasonal flu and not swine flu... the extent which the findings can be applied to the current pandemic is questionable.
"Whilst there is a doubt about how swine flu affects children, we believe a safety-first approach of offering anti-virals to everyone remains a sensible and responsible way forward."
(JM/BMcC)
Related UK National News Stories
Click here for the latest headlines.
23 July 2009
Swine Flu Line To Be Launched As 100,000 Further People Are Diagnosed
The number of those diagnosed with swine flu in the last seven days has reached 100,000 - more than double of the total the previous week in England.
Swine Flu Line To Be Launched As 100,000 Further People Are Diagnosed
The number of those diagnosed with swine flu in the last seven days has reached 100,000 - more than double of the total the previous week in England.
19 October 2005
Flu jabs planned for all Britons
The government has announced plans to vaccinate everyone in the UK in the event of a flu pandemic. Chief Medical Officer Sir Liam Donaldson announced that the Department of Health is inviting manufacturers to tender for a contract to supply pandemic flu vaccine.
Flu jabs planned for all Britons
The government has announced plans to vaccinate everyone in the UK in the event of a flu pandemic. Chief Medical Officer Sir Liam Donaldson announced that the Department of Health is inviting manufacturers to tender for a contract to supply pandemic flu vaccine.
17 November 2011
Flu Vaccination Delayed For 'More Advice'
The Department of Health has said on Thursday that it needs further advice from the committee looking into the flu vaccine before it can roll out a larger programme. The announcement follows a request from Health Secretary Andrew Lansley to look at whether the flu vaccination programme should be extended to healthy children.
Flu Vaccination Delayed For 'More Advice'
The Department of Health has said on Thursday that it needs further advice from the committee looking into the flu vaccine before it can roll out a larger programme. The announcement follows a request from Health Secretary Andrew Lansley to look at whether the flu vaccination programme should be extended to healthy children.
05 February 2010
Swine Flu Vaccine 'Still Vital'
Swine flu cases remain near their lowest level since the early stages of the disease in the UK, according to a statistical bulletin from the Chief Medical Officer for England, published today.
Swine Flu Vaccine 'Still Vital'
Swine flu cases remain near their lowest level since the early stages of the disease in the UK, according to a statistical bulletin from the Chief Medical Officer for England, published today.
03 October 2011
'Get Flu Jab' Urges Top Medic
It has been claimed that people "are playing Russian roulette with their lives" every year by not protecting themselves against seasonal flu. The Chief Medical Officer has also warned people to get vaccinated against yellow fever, typhoid and hepatitis A before jetting off on exotic holidays to Thailand or Africa.
'Get Flu Jab' Urges Top Medic
It has been claimed that people "are playing Russian roulette with their lives" every year by not protecting themselves against seasonal flu. The Chief Medical Officer has also warned people to get vaccinated against yellow fever, typhoid and hepatitis A before jetting off on exotic holidays to Thailand or Africa.