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16/03/2006
Drug trial men remain seriously ill
Two volunteers who fell ill after participating in the trial of a new drug remain in a critical condition.
Six men fell ill after participating in the trial of anti-inflammatory drug TGN 1412 at a research unit at the Northwick Park Hospital on Monday. Four of the men are now understood to be improving, although they are still seriously ill.
One of the men who is critically ill has been named as 21-year-old student Ryan Wilson, from Highbury, north London. One of the other volunteers is understood to be from New Zealand.
The trial, which was being conducted by American firm Parexel, was suspended by the Medical and Healthcare Products Regulatory Agency and an investigation has been launched into the testing procedures to see what caused the severe reaction.
TeGenero, the company which manufactured the drug, denied allegations that animals had died during previous drug tests. Chief scientific officer Thomas Hanke also confirmed that the firm had apologised to the relatives of the sick men.
Two of the men were given placebos during the trial and did not suffer any ill effects. One of the men, Raste Khan, gave an interview to 'The Sun' newspaper describing the scenes at the research unit after the men had taken the drug. Mr Khan described how the other patients began vomiting, fainting and screaming in agony. He told the newspaper that the men "went down like dominos". "First they began tearing their shirts off complaining of fever, then some screamed out that their heads felt like they were about to explode," Mr Khan told 'The Sun'.
Monday's trial was the first time that TGN 1412 had been tested on humans.
(KMcA/GB)
Six men fell ill after participating in the trial of anti-inflammatory drug TGN 1412 at a research unit at the Northwick Park Hospital on Monday. Four of the men are now understood to be improving, although they are still seriously ill.
One of the men who is critically ill has been named as 21-year-old student Ryan Wilson, from Highbury, north London. One of the other volunteers is understood to be from New Zealand.
The trial, which was being conducted by American firm Parexel, was suspended by the Medical and Healthcare Products Regulatory Agency and an investigation has been launched into the testing procedures to see what caused the severe reaction.
TeGenero, the company which manufactured the drug, denied allegations that animals had died during previous drug tests. Chief scientific officer Thomas Hanke also confirmed that the firm had apologised to the relatives of the sick men.
Two of the men were given placebos during the trial and did not suffer any ill effects. One of the men, Raste Khan, gave an interview to 'The Sun' newspaper describing the scenes at the research unit after the men had taken the drug. Mr Khan described how the other patients began vomiting, fainting and screaming in agony. He told the newspaper that the men "went down like dominos". "First they began tearing their shirts off complaining of fever, then some screamed out that their heads felt like they were about to explode," Mr Khan told 'The Sun'.
Monday's trial was the first time that TGN 1412 had been tested on humans.
(KMcA/GB)
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28 March 2006
Drug trial pair released from hospital
Two of the six men who were hospitalised after a drugs trial went wrong have been allowed to return home. Doctors at Northwick Park Hospital said that the two men had responded "very well" to treatment and had made an "excellent recovery". However, four men remain in hospital.
Drug trial pair released from hospital
Two of the six men who were hospitalised after a drugs trial went wrong have been allowed to return home. Doctors at Northwick Park Hospital said that the two men had responded "very well" to treatment and had made an "excellent recovery". However, four men remain in hospital.
20 March 2006
Company admits trial drug caused side effects in monkeys
The drug which has left six men seriously ill in hospital during a trial caused glands in two monkeys to swell during earlier tests, it has been revealed. However, TeGenero, the German company that manufactured the TGN1412 drug, said that the symptoms shown by the monkeys differed from those suffered by the men during the trial last week.
Company admits trial drug caused side effects in monkeys
The drug which has left six men seriously ill in hospital during a trial caused glands in two monkeys to swell during earlier tests, it has been revealed. However, TeGenero, the German company that manufactured the TGN1412 drug, said that the symptoms shown by the monkeys differed from those suffered by the men during the trial last week.
05 April 2006
Drugs trial 'followed correct protocols'
An investigation into the drugs trial which left six men seriously ill in hospital has ruled that the trial followed the agreed protocol. The Medicines and Healthcare Products Regulatory Agency report said that there was nothing in the way the trial was run which contributed to the adverse reactions suffered by the volunteers.
Drugs trial 'followed correct protocols'
An investigation into the drugs trial which left six men seriously ill in hospital has ruled that the trial followed the agreed protocol. The Medicines and Healthcare Products Regulatory Agency report said that there was nothing in the way the trial was run which contributed to the adverse reactions suffered by the volunteers.
15 March 2006
Six men hospitalised after drug trial
Six men are in intensive care after falling ill during trials of a new anti-inflammatory drug.
Six men hospitalised after drug trial
Six men are in intensive care after falling ill during trials of a new anti-inflammatory drug.
19 April 2006
Drug trial victims offered £5,000
Six volunteers who participated in a drug trial which left them seriously ill have been offered interim payments of £5,000 if they agree not to sue. Lawyers for four of the six men said that the manufacturer of the drug, TeGenero, had agreed to pay the men compensation on the condition that they accepted a “no-fault” procedure.
Drug trial victims offered £5,000
Six volunteers who participated in a drug trial which left them seriously ill have been offered interim payments of £5,000 if they agree not to sue. Lawyers for four of the six men said that the manufacturer of the drug, TeGenero, had agreed to pay the men compensation on the condition that they accepted a “no-fault” procedure.
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