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25/06/2014
Breakthrough In Cystic Fibrosis Study
A scientist from Queen's University Belfast has played a key role in the development of treatment for cystic fibrosis sufferers.
Professor Stuart Elborn, alongside colleagues from the United States and Australia, has helped to develop a combination therapy that improves lung function and reduces hospitalisations for patients with the most common type of cystic fibrosis.
The medication, Ivacaftor, is the first drug to treat the underlying causes of cystic fibrosis rather than just the symptoms. It is currently approved for patients with the 'celtic gene' mutation, which is carried by around 4% of all patients, and up to 15% of patients in Ireland.
Professor Stuart Elborn, Dean of the School of Medicine, Dentistry and Biomedical Sciences at Queen's University Belfast, and the European lead on the study, explained: "This is a very significant breakthrough for people with cystic fibrosis. While we had previously found an effective treatment for those with the 'celtic gene' this new combination treatment has the potential to help roughly half of those with cystic fibrosis, those who have two copies the F508DEL mutation.
"This is another example of how Queen's scientists are working internationally to change lives around the world."
Cystic fibrosis is a fatal lung disease affecting 75,000 children and adults world-wide, and is caused by inherited genetic mutations that vary among different patient groups.
(JP)
Professor Stuart Elborn, alongside colleagues from the United States and Australia, has helped to develop a combination therapy that improves lung function and reduces hospitalisations for patients with the most common type of cystic fibrosis.
The medication, Ivacaftor, is the first drug to treat the underlying causes of cystic fibrosis rather than just the symptoms. It is currently approved for patients with the 'celtic gene' mutation, which is carried by around 4% of all patients, and up to 15% of patients in Ireland.
Professor Stuart Elborn, Dean of the School of Medicine, Dentistry and Biomedical Sciences at Queen's University Belfast, and the European lead on the study, explained: "This is a very significant breakthrough for people with cystic fibrosis. While we had previously found an effective treatment for those with the 'celtic gene' this new combination treatment has the potential to help roughly half of those with cystic fibrosis, those who have two copies the F508DEL mutation.
"This is another example of how Queen's scientists are working internationally to change lives around the world."
Cystic fibrosis is a fatal lung disease affecting 75,000 children and adults world-wide, and is caused by inherited genetic mutations that vary among different patient groups.
(JP)
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30 October 2013
Queen's Joins Cystic Fibrosis Research Programme
Scientists at Queen's University Belfast are taking part in a new €6m bid to find treatments for Cystic Fibrosis. Professor Stuart Elborn will lead the study at Queen's University, which is the lead partner in the new research programme.
Queen's Joins Cystic Fibrosis Research Programme
Scientists at Queen's University Belfast are taking part in a new €6m bid to find treatments for Cystic Fibrosis. Professor Stuart Elborn will lead the study at Queen's University, which is the lead partner in the new research programme.
14 January 2022
Health Minister Confirms Extension To Use Of Cystic Fibrosis Treatment
Health Minister Robin Swann has announced that Kaftrio will be made available to suitable patients aged six years and older in Northern Ireland for the treatment of cystic fibrosis (CF).
Health Minister Confirms Extension To Use Of Cystic Fibrosis Treatment
Health Minister Robin Swann has announced that Kaftrio will be made available to suitable patients aged six years and older in Northern Ireland for the treatment of cystic fibrosis (CF).
14 August 2024
Grand Central Construction Team To Raise Funds For Cystic Fibrosis Trust
Ten members of the construction team delivering Belfast Grand Central Station are to participate in a 48-hour cycling challenge to raise funds on behalf of Cystic Fibrosis Trust. The group of amateur cyclists from joint venture Farrans Sacyr, will set out from Glasgow on 21 September and aim to reach Fort William, 104 miles away, in just 48 hous.
Grand Central Construction Team To Raise Funds For Cystic Fibrosis Trust
Ten members of the construction team delivering Belfast Grand Central Station are to participate in a 48-hour cycling challenge to raise funds on behalf of Cystic Fibrosis Trust. The group of amateur cyclists from joint venture Farrans Sacyr, will set out from Glasgow on 21 September and aim to reach Fort William, 104 miles away, in just 48 hous.
26 January 2005
Funding secured for cystic fibrosis researchers
Cystic fibrosis researchers from Queen's University have won a share of a major £500,000 funding grant. The Cystic Fibrosis Trust was awarded £509,759 from the Big Lottery Fund to help improve the lives of disadvantaged children and young adults with the disease.
Funding secured for cystic fibrosis researchers
Cystic fibrosis researchers from Queen's University have won a share of a major £500,000 funding grant. The Cystic Fibrosis Trust was awarded £509,759 from the Big Lottery Fund to help improve the lives of disadvantaged children and young adults with the disease.
13 November 2019
CF Drugs To Be Available Within Weeks
Clinicians will begin prescribing life-changing drugs to local Cystic Fibrosis patients in a matter of weeks, the Department of Health has confirmed. Orkambi, Symkevi and Kalydeco will be made available through a deal with manufacturer Vertex Pharmaceuticals which follows similar arrangements in England and Scotland.
CF Drugs To Be Available Within Weeks
Clinicians will begin prescribing life-changing drugs to local Cystic Fibrosis patients in a matter of weeks, the Department of Health has confirmed. Orkambi, Symkevi and Kalydeco will be made available through a deal with manufacturer Vertex Pharmaceuticals which follows similar arrangements in England and Scotland.
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